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Mapping singlecell atlases throughout Metazoa unravels cell type ...
SAMaplinked gene pairs that are enriched in cell type pairs between S. mediterranea and S. mansoni. (A) Rows: linked cell types. Schistosome cell types correspond to Leiden clusters. Columns: genes linked by SAMap with overlapping eukaryotic eggNOG orthology groups. We calculate the average standardized expression of each gene in an orthology ...
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Cell type matching across species using protein embeddings and transfer ...
ADS and recall for TACTiCS, Seurat, and SAMap on human, mouse, and marmoset.
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Cell type matching across species using protein embeddings and transfer ...
The performance of SAMap and Seurat for the speciesspecific cell types is not consistent across all cell types and comparisons. For example, SAMap correctly assigns zero scores to mouse Meis2, Peri, and SMC in the humanmouse comparison, but incorrectly matches mouse SMC to marmoset Peri with a high matching score.
The Official WhitepagesMapping singlecell atlases throughout Metazoa unravels cell type ...
SAMap iterates between two modules. The first module constructs a genegene bipartite graph with crossspecies edges connecting homologous gene pairs, initially weighted by protein sequence similarity ().In the second module, SAMap uses the genegene graph to project the two singlecell transcriptomic datasets into a joint, lowerdimensional manifold representation, from which each cell's ...
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The System for Award Management (SAM) is the Official Government system that consolidated the capabilities of CCR/FedReg, ORCA, and EPLS
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Smithsonian Acquires Rare Photographs From the First African American ...
The group of 286 objects, dating from the 1840s to the mid1920s, includes a cache of 40 daguerreotypes made by three of the most prominent Black photographers of the 19th century, James P. Ball ...
Joint profiling of gene expression and chromatin accessibility during ...
Ma et al. conduct a joint profiling of gene expression and chromatin accessibility during amphioxus embryogenesis at singlecell resolution. With the datasets generated, a developmental tree for amphioxus cell fate commitment and lineage specification is constructed, and multiple markers for each lineage are identified and validated.